T1DBase Summary

T1DBase is a public website and database that supports the type 1 diabetes (T1D) research community. It is being created by a joint effort between the Institute for Systems Biology, Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory and the Juvenile Diabetes Research Foundation International. T1DBase collects information from public sources and from collaborating laboratories, integrates this information, and presents it in a form that is useful for T1D researchers. The current data includes annotated genomic sequences for suspected T1D susceptibility regions; microarray data; functional annotation of genes active in beta cells; and "global" datasets, generally from the literature, that are useful for systems biology studies. The site also includes software tools for analyzing the data.

The search engine is one of the main entry points to T1DBase. The home page has a search box in the centre of the page, and each individual page on T1DBase has a search box in the red title bar on the right.

The search database currently contains:

• Genes from the Beta Cell Gene Expression Bank
• Genes from the rest of the T1DBase Website
• Type 1 diabetes candidate regions
• Markers from dbSNP

Genes can be searched via

• Beta Cell Gene Expression Bank identifiers: Unigene ID, Sequence ID, Gene Symbol, Affymetrix Probeset ID
• Gene identifiers: Gene Symbol, Unigene ID, Entrez Gene ID, HomoloGene ID, OMIM ID, EPConDB DoTS ID, RefSeq ID or Gene Cards ID
• Candidate Region identifiers: Candidate Region Name, Candidate Region band location, RGD QTL ID
• Marker identifiers: RS ID, SS ID, Population Name
• Currently, only single-identifier searches are supported (lists will be supported in the future)
• Search results will be returned in a table with a section for each object type, a link to the page about the object and a summary of available information.

Return to Table 1.

  Related websites: Main HuGENet site | Greece Coordinating Centre | Canada Coordinating Centre