PharmGKB Summary

The PharmGKB database is a central repository for genetic, genomic, molecular and cellular phenotype data and clinical information about people who have participated in pharmacogenomics research studies. Its aim is to aid researchers in understanding how genetic variation among individuals contributes to differences in reactions to drugs. The data include, but are not limited to, clinical and basic pharmacokinetic and pharmacogenomic research in the cardiovascular, pulmonary, cancer, pathways, metabolic and transporter domains. The contributors tab contains the links to all of the projects submitting data to the PharmGKB.

The PharmGKB welcomes submissions of primary data from all research into genes and genetic variation and their effects on drug and disease phenotypes.

Pharm GKB is searchable via 6 different fields, genes (all/with PharmGKB primary data/with genotype data/ with literature annotations), diseases (all/ diseases with primary PharmGKB data) pathways, drugs (all/ drugs with PharmGKB primary data), submissions (by project/ by submitter/ other) or variants.

Results for the gene searches return a page with information on the gene, the number of positions analysed, phenotype datasets, pathways, literature annotations and other information. The page also contains links to OMIM, Entrez Gene, UCSC and Ensembl genome browsers, GDB, GO, Gene Atlas, Gene cards, MutDB, Promolign, NCBI Reference sequences, SOURCE and Swissprot in addition to a link enabling the download of primary data.

Return to Table 1.

  Related websites: Main HuGENet site | Greece Coordinating Centre | Canada Coordinating Centre