Simon Sanderson - Staff Page

Title:
Consultant Senior Research Associate and Clinical Lecturer in Primary Care Genetics

Address:
General Practice & Primary Care Research Unit
Department of Public Health and Primary Care
University of Cambridge
University Forvie Site
Robinson Way
Cambridge CB2 2SR

Email: Simon Sanderson

Background:
Simon was the gold medalist student of his class, graduating from Bristol University in 1989.  His initial training was in hospital medicine, followed by public health medicine in Cambridge until 1996.  He then became a principal in general practice, working in South East England and London until 2002, when he returned to Cambridge as Clinical Lecturer in Primary Care Genetics.  He is also a consultant in public health medicine, working in the PHG Foundation (formerly the Public Health Genetics Unit) in Cambridge, and was recently appointed as senior research associate in the General Practice and Primary Care Research Unit.

Current Research Interests and Activities:
His primary research interests are the genetic epidemiology of cardiovascular disease, meta-analysis of genetic association studies, and methodological issues in the evaluation of genetic tests.  He also provides clinical support to the Unit's diabetes trials (ADDITION and DICISION).

Publications:
Sanderson SP, Zimmern R, Kroese M, Higgins J, Patch C, Emery J. How can the evaluation of genetic tests be enhanced? Lessons learned from the ACCE framework and UK experience. Genet Med 2005;7:495-500.

Sanderson SP, Emery J, Baglin T, Kinmonth AL. Aspirin resistance: a review of the phenomenon and its clinical implications. Annals Int Med 2005;142:370-380

Sanderson SP, Emery J, Higgins JPT. CYP2C9 gene variants and clinical outcomes in warfarin- treated patients: a HuGE systematic review and meta-analysis. Genet Med 2005;7:97-104

Salanti G, Sanderson SP, Higgins JPT. Obstacles and opportunities in the meta-analysis of genetic association studies. Genet Med 2005;7:13-20

Kroese M, Zimmern R, Sanderson SP. Genetic tests and their evaluation: can we answer the key questions? Genet Med 2004;6:475-480

Sanderson S, Salanti G, Higgins JPT. Joint effects of NAT1, NAT2 genes and smoking on bladder carcinogenesis: a HuGE literature-based systematic review and evidence synthesis. American Journal of Epidemiology [in press]

Sanderson S, Tatt I, Higgins JPT. Tools for assessing quality and susceptibility to bias: a systematic review and annotated bibliography. International Journal of Epidemiology [in press]

Iyer S, Sanderson S et a. Array-based comparative genomic hybridisation for investigating patients with learning disability: systematic review meta-analysis of diagnostic yield and false positive results. Genetics in Medicine 2007;9:74-79.

Burton H, Sanderson S, Shortland G, Lee P. Needs assessment and review of services for patients with inherited metabolic disease in the UK. Journal of Inherited Metabolic Disease 2006 29:667-676

Sanderson S, Green A, Preece MA, Burton H. The frequency of inherited metabolic disorders in the West Midlands, United Kingdom. Archives of Disease in Childhood 2006; 91:896-899

Brice P, Sanderson S. Genetics, Health and Medicine. The Pharmaceutical Journal 2006;277:53-56

Brice P, Sanderson S. Uses for genetics in pharmacy. The Pharmaceutical Journal 2006;277:109-112

Sanderson S, Brice P. Pharmacogenetics: what are the ethical and economic implications? The Pharmaceutical Journal 2006;277:113-114